Dr Eilís Dowd awarded funding from the Michael J Fox Foundation

Dr Eilís Dowd,  Senior Lecturer at NUI Galway and president of Neuroscience Ireland, has been awarded funding of US$300,000 from The Michael J Fox Foundation for Parkinson’s Research to develop a novel approach to brain repair for Parkinson’s disease.

Click here to view Dr Dowd’s interview about the research funding on Ireland AM 

Parkinson’s is a condition that primarily affects a person’s ability to control movement leading to a progressive deterioration in ability. The symptoms of the condition are caused by the degeneration and death of brain cells that regulate movement.

 

Brain repair for Parkinson’s involves replacing these dead cells by transplanting healthy brain cells into the brain, but the widespread roll-out of this therapy has been hindered by the poor survival of the implanted cells.

In research that made global headlines recently, Dr Eilís Dowd’s research team demonstrated that the survival of the cells was dramatically improved when they were implanted into the brain within a supportive gel made from the natural material collagen. The funding from The Michael J Fox Foundation will allow Dr Dowd to take this research to the next level where she will test if the collagen gel can also improve the survival of healthy brain cells generated from adult stem cells.

Commenting on the funding award, Dr Eilís Dowd at NUI Galway, said: “In our previous research published in the Nature journal, Scientific Reports, we showed that collagen provides the cells with a nurturing, supportive environment in the brain and helps them to survive the aversive transplant process. This funding from The Michael J Fox Foundation will allow us to test if this approach can also improve survival and reparative ability of healthy brain cells derived from adult stem cells. If so, this could lead to a dramatic improvement in brain repair approaches for Parkinson’s – a field that has been hampered for years by poor transplant survival.”

The Michael J Fox Foundation is dedicated to finding a cure for Parkinson’s disease and to ensuring the development of improved therapies for those living with Parkinson’s today.

 

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